Computer Scientist/Software Engineer

Greenville Neuromodulation Center (GNC) has an immediate opening for a computer scientist/software engineer.  GNC is a private non-profit corporation in Greenville, PA USA whose mission is to advance neuromodulation therapies, particularly Deep Brain Stimulation (DBS) through patient care, technology development, research, education, and training.  The computer scientist/engineer would be working in collaboration with Dr. Erwin Montgomery (PubMed bibliography at

Our research and technology development exploits the electrophysiological mechanisms underlying brain function in health and disease.  Much of our work involves developing analytical tools for understanding signals generated in the nervous system and how electrical stimulation of the nervous system affects brain function.  Both efforts ultimately are directed to improving neurological and psychiatric disorders.

One of our major efforts in developing a completely automated system for neurophysiological mapping of targets for implantation of chronic stimulating electrodes.  Hopefully, these systems will reduce the technical prerequisites for offering DBS lead implantation surgery thereby allowing more patients to benefit.

GNC collaborates with Thiel College.   The computer scientist will participate in various educational and research programs with the students, faculty and administration of Thiel College.

Below are references to patents and publications specifically related to our development efforts.


  • Methods for identifying neuronal spikes  US 7957793 B2
    •  Apparatus and methods for evaluating a patient  WO 2012018543 A3
  • Neuron signal analysis system and method  US 7136696 B2
  • Intraventricular electrodes for electrical stimulation of the brain  US 20090125080 A1
  • Methods and devices for analysis of clustered data, in particular action potentials (i.e. neuron firing signals in the brain)  US 8150795 B2
  • Method and system for physiological target localization from macroelectrode recordings and monitoring spinal cord function


  • Takeshita, D., Gale, J.T., Montgomery, E.B. Jr., Bahar, S., Moss, F. Analyzing spike trains with circular statistics American Journal of Physics. 77(5) 424-429
  •  Montgomery EB Jr, Gale JT, Huang H. Methods for isolating extracellular action potentials and removing stimulus artifacts from microelectrode recordings of neurons requiring minimal operator intervention. J Neurosci Methods.   2005 May 15;144(1):107-25. Epub 2004 Dec 13. PubMed PMID: 15848245.
  • Montgomery EB Jr, Huang H, Assadi A. Unsupervised clustering algorithm for N-dimensional data. J Neurosci Methods. 2005 May 15;144(1):19-24. Epub 2004 Dec 18. PubMed PMID: 15848235.

Position Requirements

  •  Master’s degree in computer science
  •  Proficiency in
    • Designing computation algorithms and architectures
    • MS Visual Studio 2010 and later
    • C-based programming languages – C/C++ and C#
    • Internet and website programming
    • SQL and other databases
    • Matlab
  • Knowledge of basic statistics
  • Familiarity with time series statistical analyses
  • Competence in computer-hardware interfacing
  • Competence in basic maintenance of computer hardware and software systems
  • Have a basic knowledge of neurophysiology and electroneurophysiological clinical and research techniques
  • Ability to work independently
  • Ability to work effectively in a team with diverse interests and knowledge
  • Work with patients and human research subjects
  • Assist in animal-based research
  • Dedication to the mission of GNC

Interested candidates should send a letter of interest and curriculum vitae (CV) or resume by e-mail or regular mail to:

Greenville Neuromodulation Center, 179 Main St., Greenville, PA 16125